Also, keep an eye on our College Football Odds page for the latest up-to-date betting lines. Alabama Poised For Back-to-Back Titles The Crimson Tide were unstoppable in the 2020-21 season, running the table with a 13-0 season culminating in a national championship. On The Money: A Look at the Betting Lines and Trends for Ohio State, Clemson and the College Football Playoff By Matt Gutridge on December 26, 2020 at 5:00 pm @remybuckeye 2021 Sugar Bowl.

• Clemson Football Betting Line
• Osu Football Betting Line
• Uconn Football Betting Line

UPDATE (Thursday at 8:35 p.m. ET): Clemson QB Trevor Lawrencereportedly tested positive for COVID-19 Thursday. Odds were taken off the board.

The Boston College Eagles (4-2, 3-2 ACC) and Clemson Tigers (6-0, 5-0) meet at Memorial Stadium in Clemson, S.C., for a noon ET kickoff Saturday (on ABC). Below, we analyze the Boston College-Clemson college football betting odds and lines, with picks and predictions.

The Tigers are No. 1 in the Amway Coaches Poll powered by USA TODAY Sports.

Boston College at Clemson: Betting odds and lines

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 6:14 p.m. ET.

Money line: Boston College +1400 (bet $100 to win $1,400) Clemson -5000 (bet $5,000 to win $100)Against the spread/ATS: Boston College +31.5 (-115) Clemson -31.5 (-106)Over/Under: 60.5 (O: -115 U: -106)

Boston College at Clemson: Three things to know

The Eagles are coming off their most impressive offensive showing of the season, routing visiting Georgia Tech by a 48-27 count. While they’re 3-1 SU/ATS in four games at home, they were routed in their most recent road trip to Virginia Tech 40-14 on Oct. 17.The Tigers were a little sluggish for a good chunk of last week’s game against Syracuse. Just don’t ask HC Dabo Swinney about it, or you’ll get an earful like some poor reporter did after the game. Google it. Anyway, the Tigers are still 6-0 SU. They beat the Orange 47-21 last week, so it’s not like they were awful. Overall, they’re 2-4 ATS, including 1-3 ATS in four games at home.Clemson’s offense continues to impress, posting 518.0 total yards (10th in the country), 341.3 passing yards (11th) and 48.2 points (4th) per game. Defensively, the Tigers are equally strong, allowing just 274.7 total yards (10th), 169.3 passing yards (11th) and 105.3 rushing yards (19th) with 13.5 points (12th) per game.

Get some action on this game or any other matchup with a legal, online bet at BetMGMin CO, IN, NJ and WV. Risk-free first bet up to $500, paid in free bets. Terms and conditions apply. Bet now!

Boston College at Clemson: Odds, prediction, betting lines and picks

Prediction

Clemson 45, Boston College 17

Money line (ML)

PASS. Clemson will win, but it’s definitely not wise to risk 50 times your potential return.

Against the spread (ATS)

BOSTON COLLEGE (+31.5, -115) has the passing attack to at least keep Clemson within four touchdowns. QB Phil Jurkovec has completed 62.5 percent of his passes for 1,671 yards, 12 touchdowns and just four interceptions through six games, and he has rushed for three more scores. He is no Heisman Trophy candidate like Clemson QB Trevor Lawrence, but Jurkovec might be one of the more unheralded quarterbacks in the ACC.

Over/Under (O/U)

OVER 60.5 (-115) is worth a small-unit wager. The Under is 6-1 in BC’s past seven as an underdog, and an impressive 44-18-2 in the past 64 on the road for the Eagles. In addition, the Under has hit in six of the previous eight meetings at Death Valley.

Want some action in this one? Place a bet at BetMGM now. For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow @JoeWilliamsVI on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional college football coverage from USA TODAY Sports Media Group:

Alabama football / Auburn football / Florida football / Georgia football / LSU football / Michigan football / Michigan State football / Notre Dame football / Ohio State football / Oklahoma football / Tennessee football / Texas football / USC football / Wisconsin football

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage.

No. 1 Clemson is expected to get past struggling Syracuse on Saturday rather handily, according to the betting odds.

The Tigers are favored by 46 points over the Orange, who suffered a 38-21 loss at home to Liberty last week, dropping them to 1-4. Clemson, on the other hand, is rolling at 5-0 and coming off a 73-7 beatdown of Georgia Tech. The Tigers are outscoring their opponents by an average of 36.6 points per game.

The odds on Clemson beating Syracuse straight up are so ridiculous that most sportsbooks aren't offering a money-line price on the game. FanDuel, however, is, and has the Tigers listed at -100,000 to win outright, while Syracuse is +4,000 (40-1) to pull off the upset.

Clemson Football Betting Line

That's right. If you want to bet on Clemson to beat Syracuse, you'd need to put up $1,000 to win $1 at FanDuel, one of the only U.S. sportsbooks to offer a money-line price on the seemingly lopsided matchup.

And someone did.

According to FanDuel, a bettor placed an $8,600 money-line bet on Clemson at -100,000 odds. If the Tigers prevail, the bettor will add $8.60 to his bankroll.

The largest bet on Syracuse was $50 at 40-1. As of Friday afternoon, there had been three times as many money-line bets on the Orange as there were on Clemson, but the Tigers had attracted 92% of the money, thanks primarily to the $8,600 wager.

'Obviously, the probability of Clemson winning the game is huge, but people want to have a bet on what would be one of the greatest upsets in college football,' John Sheeran, FanDuel's sportsbook director, told ESPN.

Osu Football Betting Line

The point spread, at Clemson -46, is the largest line on an ACC game since Florida State was a 48-point favorite over Wake Forest in 2000. The money-line price is among the largest ever posted by a U.S. sportsbook as well.

Even the sportsbook at South Point casino and hotel in Las Vegas, which has been known to put up money-line prices on big college football favorites in the past, chose to hold off on the Syracuse-Clemson game.

Uconn Football Betting Line

'This one's just too big,' South Point sportsbook director Chris Andrews said.